Yep, it does. Pump specs, as opposed to what is actually delivered at the injector pump is the issue from memory. My old Walbro, rated at 5 psi, only delivered about 1psi at the pump, nowhere near enough.Does a TD42 need that much flow and fuel pressure? Carter 4600 yeah no problem. They even run fine with a Facet pump.
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No doubt the motor spec is a factor too, with 12mm pumps benefiting from the larger lift pump. In my case Oldmav advised getting the 4601. I think Geeyoutoo uses one on his ZD also. As you say, the 4600 would be fine too for many people.